Status:

UNKNOWN

Effects of Recombinant Human Thrombopoietin on Platelet Levels in ICU Patients

Lead Sponsor:

Nanfang Hospital, Southern Medical University

Collaborating Sponsors:

The Third Affiliated Hospital of Southern Medical University

The Second People's Hospital of GuangDong Province

Conditions:

Pneumonia

Thrombocytopenia

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The incidence of thrombocytopenia in ICU patients with severe illness ranged from 8.3% to 67.6%, and ranged from 14% to 44% during ICU treatment.Severe patients with thrombocytopenia also have signifi...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of pneumonia (community acquired pneumonia, hospital acquired pneumonia or ventilator associated pneumonia);
  • Voluntarily signed informed consent;
  • ≥18 years old;
  • Platelet count ≤75×109/L

Exclusion

  • A history of hematopoietic stem cell transplantation or solid organ transplantation such as liver, kidney or lung;
  • Hematological malignancy;
  • Immune thrombocytopenia, such as SLE, ITP, TTP, etc.
  • The length of stay in ICU is less than 24h;
  • Pregnant or lactation patients;

Key Trial Info

Start Date :

February 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2023

Estimated Enrollment :

178 Patients enrolled

Trial Details

Trial ID

NCT05217719

Start Date

February 1 2022

End Date

October 1 2023

Last Update

February 1 2022

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