Status:
UNKNOWN
Association Between Persistent Organic Pollutants and Type 2 Diabetes /Thyroid Cancer
Lead Sponsor:
Qianfoshan Hospital
Collaborating Sponsors:
Chinese Academy of Sciences
Conditions:
Type 2 Diabetes
Thyroid Cancer
Eligibility:
All Genders
18-75 years
Brief Summary
Persistent organic pollutants (POPs) are a class of organic pollutants in the environment characterized by persistent, bioaccumulation, long-range transport and biological toxicity. Due to its widespr...
Eligibility Criteria
Inclusion
- Group of Type 2 diabetes patients:
- age 18 \~ 75 years old;
- type 2 diabetes patients diagnosed in the First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province) , HBA1C ≥7.0% and \<10.5% ;
- patients signed informed consent.
- Group of Thyroid Cancer patients:
- age 18 \~ 75 years old;
- thyroid cancer patients diagnosed in the First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province) ;
- patients who signed the informed consent form.
- Control Group:
- age 18 \~ 75 years old;
- healthy population recruited from the First Affiliated Hospital of Shandong First Medical University (Qianfoshan Hospital of Shandong Province) ;
- living in the monitoring area for more than 6 months within 12 months;
- normal thyroid function and no history of thyroid cancer were needed in the control group;
- Fasting Blood Glucose level of 0.7 mmol/l was needed in the Control Group of Type 2 diabetes Mellitus Without History of diabetes;
- patients with informed consent.
Exclusion
- Group of Type 2 diabetes:
- (1) pregnant, lactating women, patients with acute cardiac cerebrovascular disease; (2) patients with severe liver and Renal Impairment (related laboratory tests more than 2 times the normal) ; (3) patients with Type 1 diabetes; (4) participants in other clinical trials within 3 months; (5) patients with malignant tumors. (6) has the disease and so on serious anemia, is not suitable to carry on the patient which the blood draws the test.
- Group of Thyroid Cancer:
- patients with serious heart, liver and Kidney Diseases (related laboratory tests more than 2 times normal) ;
- patients with other malignant tumors.
- Control Group:
- patients with serious heart, liver or kidney disease;
- patients with iodine or Thyroid hormone;
- patients with confirmed malignant tumor;
- pregnant women or those who have recently taken contraception or estrogen.
Key Trial Info
Start Date :
December 20 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
900 Patients enrolled
Trial Details
Trial ID
NCT05218395
Start Date
December 20 2021
End Date
December 30 2025
Last Update
February 24 2022
Active Locations (1)
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1
Xiaoling Guan
Jinan, Shandong, China