Status:

COMPLETED

A Study of Azacitidine in Participants With International Prognostic Scoring System (IPSS) Intermediate-2 and High-risk Myelodysplastic Syndromes (MDS), or Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML)

Lead Sponsor:

Bristol-Myers Squibb

Conditions:

Myelodysplastic Syndromes

Leukemia, Myelomonocytic, Chronic

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to assess the safety and effectiveness in the real-world setting among participants who are treated with Azacitidine in accordance with the China Product Label.

Detailed Description

This study will have participants both enrolled retrospectively and prospectively for azacitidine (AZA) treatment.

Eligibility Criteria

Inclusion

  • Documented diagnosis of intermediate-2/ high-risk myelodysplastic syndromes (MDS) or chronic myelomonocytic leukemia (CMML) or acute myeloid leukemia (AML) with 20-30% bone marrow blasts and multi-lineage dysplasia
  • Initiated azacitidine (AZA) treatment per approved China Product Label after April 2017

Exclusion

  • Contraindicated for the use of AZA according to China Product Label
  • Simultaneously participating in a treatment intervention study
  • Other protocol-defined inclusion/exclusion criteria apply.

Key Trial Info

Start Date :

February 25 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 20 2023

Estimated Enrollment :

290 Patients enrolled

Trial Details

Trial ID

NCT05218902

Start Date

February 25 2022

End Date

March 20 2023

Last Update

May 31 2023

Active Locations (1)

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Local Institution - 0001

Tianjin, Tianjin Municipality, China, 300010

A Study of Azacitidine in Participants With International Prognostic Scoring System (IPSS) Intermediate-2 and High-risk Myelodysplastic Syndromes (MDS), or Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML) | DecenTrialz