Status:
TERMINATED
The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth
Lead Sponsor:
Nour Ammar, BDS
Conditions:
Primary Teeth
Microbial Colonization
Eligibility:
All Genders
1-12 years
Phase:
PHASE3
Brief Summary
To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).
Detailed Description
Fifty children aged 4 to 6 years old with active dentin caries lesions (score 5 according to International Detection and Assessment System (ICDAS II) criteria) will be enrolled in the study. They will...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- The presence of at least one active carious lesion on a primary tooth.
- Completion of an informed consent to participate in the study.
- Exclusion criteria:
- Children reporting spontaneous or elicited pain from caries or showing any signs of pulpal infection, swelling, abscess, obvious discoloration of the tooth, or premature mobility.
- Reported usage of local or systemic antibiotics, chlorhexidine or fluoride mouthwashes within the last 2 weeks.
- Children presenting with special health care needs or undergoing medical treatment for chronic or acute diseases affecting salivary flow.
- Allergy or sensitivity to silver or any of the materials included in the study.
- Child weight less than 10 Kg (to avoid concerns for toxicity).
Exclusion
Key Trial Info
Start Date :
March 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 15 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05221749
Start Date
March 15 2022
End Date
June 15 2022
Last Update
August 18 2023
Active Locations (1)
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1
Faculty of Dentistry, Alexandria Univeristy
Alexandria, Egypt