Status:
RECRUITING
Platelet Rich Plasma for Uterine Scar
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborating Sponsors:
Sheba Medical Center
Conditions:
Cesarean Section Complications
Uterine Bleeding
Eligibility:
FEMALE
18-52 years
Phase:
NA
Brief Summary
When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing. Pla...
Detailed Description
Introduction Platelets are cytoplasmic fragments of megakaryocytes, formed in the marrow and approximately 2 μm in diameter. When vessel wall injury occurs, they become activated, releasing more than...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Women undergoing elective cesarean delivery
- Term pregnancy (≥37 weeks of gestation)
- Exclusion criteria:
- Thrombocytopenia (CBC Platelet count \<70,000)
- Connective tissue disease
- Uterine scars other than cesarean (s/p myomectomy, s/p cornual resection)
- Malformed uterus (unicornuate, bicornuate, didelphic)
Exclusion
Key Trial Info
Start Date :
July 19 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2028
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05224726
Start Date
July 19 2025
End Date
July 1 2028
Last Update
August 26 2025
Active Locations (1)
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1
Sheba Medical Center
Ramat Gan, Center, Israel, 55030