Status:
RECRUITING
tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity
Lead Sponsor:
VA Office of Research and Development
Conditions:
Obesity
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate if transcranial direct current stimulation (tDCS) can increase the effectiveness of cognitive training to reduce impulsivity in individuals with obesity, an...
Detailed Description
Two-hundred forty individuals will be screened with the goal of consenting and enrolling up to 124 patients and 88 patients completing the study. Participants completing the study will concurrently co...
Eligibility Criteria
Inclusion
- Veteran enrolled in a MOVE! Weight Management Program (group or individual) at the Minneapolis VA Health Care System
- Obese (BMI\>30 or BMI\>27 plus at least one weight-related comorbidity)
- Adults, ages 18 years or older (up to age 80)
- Able to understand English, self-consent and follow study-related procedures
- Willing to use a reliable form of birth control if they are of females of child-bearing potential
Exclusion
- History of any of the following: seizures, severe or moderate head injury, head surgery, significant neurological disorder (significance based on Principal Investigator's judgment)
- Frequent severe headaches
- History of scalp conditions such as eczema or seborrheic dermatitis
- Metal in head (other than in mouth) including shrapnel/surgical clips/welding fragments
- Implanted medical devices (including pumps and cardiac pacemakers)
- Pregnancy
- Acute substance dependence or withdrawal that would affect ability to complete cognitive training
- Moderately severe to severe depression (as identified on PHQ-9 scale during baseline screening)
- Other psychological or medical disorders requiring inpatient treatment (as identified during chart review)
- Presence of a known metabolic or hormonal disorder (such as Cushing's, untreated thyroid dysfunction, or uncontrolled diabetes mellitus defined as a hemoglobin A1c \> 8.0), or significant edema/volume overload - all of which would affect weight
- Uncontrolled hypothyroidism that would affect weight
Key Trial Info
Start Date :
November 23 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 30 2026
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT05225233
Start Date
November 23 2022
End Date
April 30 2026
Last Update
June 24 2025
Active Locations (1)
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1
Minneapolis VA Health Care System, Minneapolis, MN
Minneapolis, Minnesota, United States, 55417-2309