Status:

RECRUITING

Mapping and Characterization of Alveolar Cells During Smoking and Chronic Obstructive Disease

Lead Sponsor:

Centre Hospitalier Intercommunal Creteil

Collaborating Sponsors:

Henri Mondor University Hospital

Institut National de la Santé Et de la Recherche Médicale, France

Conditions:

Chronic Obstructive Lung Disease

Chronic Obstructive Pulmonary Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

To evaluate the regenerative capacities of mesenchymal cells composing the microenvironment of alveolar type 2 cells in a population of patients, undergoing thoracic surgery for suspected cancer, who ...

Detailed Description

Chronic obstructive pulmonary diseases (COPD) have a major public health impact, as evidenced by the 250 million patients affected by these diseases and the 50% 5-year mortality for severe stages of c...

Eligibility Criteria

Inclusion

  • Age ≥ 18
  • Patient undergoing lung resection surgery (lobectomy, pneumonectomy, segmentectomy) for cancer or suspected cancer
  • Acceptance to participate in the protocol
  • Affiliated to a social security plan

Exclusion

  • Chronic autoimmune disease
  • Patient under guardianship or curators
  • Neo-adjuvant chemotherapy
  • History of thoracic radiotherapy
  • Pregnant woman
  • Minor patient
  • Person not able to consent
  • Person deprived of liberty

Key Trial Info

Start Date :

October 5 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 5 2030

Estimated Enrollment :

186 Patients enrolled

Trial Details

Trial ID

NCT05227547

Start Date

October 5 2022

End Date

October 5 2030

Last Update

September 2 2025

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Rousseau-Bussac

Créteil, France, 94000

2

Hopital Cochin

Paris, France, 75014

3

HEGP

Paris, France, 75015

4

Hopital Tenon

Paris, France, 75020

Mapping and Characterization of Alveolar Cells During Smoking and Chronic Obstructive Disease | DecenTrialz