Status:
RECRUITING
A Randomized Trial of Imaging Selection Modalities for Stroke Thrombectomy (NO-SELECT)
Lead Sponsor:
Xinqiao Hospital of Chongqing
Collaborating Sponsors:
The First Affiliated Hospital of Hainan Medical University
Dalian Central Hospital
Conditions:
Stroke, Ischemic
Stroke, Acute
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Several studies suggest that advanced multi-modal imaging with CTP should be used to screen late time window stroke patients for thrombectomy. However, NCCT is more accessible when comparing with CTP....
Eligibility Criteria
Inclusion
- Aged 18 years or older;
- The interval time from last known well to hospital arrival is within 24 hours;
- Acute stroke confirmed by clinical symptoms or imaging examination;
- Field Assessment Stroke Triage for Emergency Destination (FAST ED) ≥4;
- Written informed consent is obtained from patients and/or their legal representatives.
Exclusion
- Allergy to radiographic contrast agents, or nitinol devices;
- Currently pregnant or lactating (women patients);
- Arterial tortuosity and/or other arterial disease that would prevent the device from reaching the target vessel;
- Preexisting neurological or psychiatric disease that would confound the neurological functional evaluations;
- Multiple vessel occlusion (e.g., bilateral anterior circulation, or occlusion of both anterior and posterior circulation);
- Brain tumors with mass effect (except meningiomas) that are radiographically pleasant;
- Intracranial aneurysm, arteriovenous malformation;
- Any terminal illness with life expectancy less than 6 months;
- Unlikely to be available for 90-day follow-up.
Key Trial Info
Start Date :
December 12 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 31 2027
Estimated Enrollment :
1846 Patients enrolled
Trial Details
Trial ID
NCT05230914
Start Date
December 12 2024
End Date
October 31 2027
Last Update
December 26 2025
Active Locations (8)
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1
Yijishan Hospital of Wannan Medical College
Wuhu, Anhui, China, 241000
2
Xinqiao Hospital of Army Medical University
Chongqing, Chongqing Municipality, China, 400037
3
Wuyi Traditional Chinese Medicine Hospital
Jiangmen, Guangdong, China, 529000
4
The First Affiliated Hospital of Hainan Medical University
Haikou, Hainan, China, 570000