Status:
UNKNOWN
Ameliorating Effects of Aging by Physical Exercise
Lead Sponsor:
Slovak Academy of Sciences
Collaborating Sponsors:
Medical University of Vienna
Conditions:
Aging
Exercise
Eligibility:
All Genders
55-85 years
Phase:
NA
Brief Summary
With increasing longevity, a significant increase in the incidence of neurodegenerative diseases is expected. According to forecasts based on data from the World Health Organization and data from epid...
Detailed Description
This interventional study will examine the effects of a comprehensive intervention associated with regular short-term (4 months) and long-term (≥2 years) exercise on the cognitive and motor functions ...
Eligibility Criteria
Inclusion
- 55-85 years of age,
- non-smokers
- complete vaccination against COVID19
- continuation in the supervised exercise program (for study of long-term effects of exercise experimental group)
- sedentary lifestyle ≥2 years prior this study (for group without intervention),
- mild cognitive impairment (for study of short-term effects of exercise experimental group)
- absence of any psychological, sociological or geographical factor that could jeopardize participation in the project.
Exclusion
- any chronic disease (oncological, cardiovascular, neurological, liver, kidney or other diseases and its acute complications at the discretion of the doctor);
- no cooperation of probands;
- insufficient functional capacity - the presence comorbidities or disorders of the musculoskeletal system, which makes it impossible to complete the training program (assessment by cardiologist, or orthopedist or other specialist);
- smoking, alcohol or drugs abuse;
- non-compliance with epidemiological measures;
- absence of complete vaccination with SARS-CoV-2 vaccine;
- presence of a pacemaker or metal implants (contraindication for magnetic resonance imaging).
Key Trial Info
Start Date :
January 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05232968
Start Date
January 10 2022
End Date
December 1 2025
Last Update
February 10 2022
Active Locations (1)
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1
Biomedical Research Center Slovak Academy of Sciences
Bratislava, Slovakia, 84505