Status:

RECRUITING

Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia

Lead Sponsor:

University Hospital, Caen

Conditions:

Regional Anesthesia Morbidity

Cesarean Section Complications

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn. Thus, intrath...

Detailed Description

The present controlled randomized double blind trial was designed to compare 2 intrathecal dose of bupivacaine for cesarean section * a "standard" dose of 10 mg of intrathecal bupivacaine associated ...

Eligibility Criteria

Inclusion

  • scheduled cesarean section with intrathecal anesthesia
  • term pregnancy \> 35 weeks
  • signed informed consent

Exclusion

  • unscheduled or emergent cesarean section
  • any contra indication to intrathecal anesthesia
  • any antihypertensive drug prescribed to control arterial pressure during pregnancy
  • pre-eclampsia and eclampsia
  • history of Marfan or Ehlers Danlos disease

Key Trial Info

Start Date :

February 23 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT05233462

Start Date

February 23 2022

End Date

December 31 2026

Last Update

July 25 2025

Active Locations (1)

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1

Caen University Hospital

Caen, France