Status:
RECRUITING
mTOR as Mediator of Insulin Sensitivity Study
Lead Sponsor:
University of Copenhagen
Collaborating Sponsors:
Danish Diabetes Academy
Conditions:
Insulin Sensitivity
Eligibility:
MALE
22-35 years
Phase:
NA
Brief Summary
The study investigates the role of mTOR in mediating enhancement of muscle insulin sensitivity following a single bout of exercise. This will be investigated in young healthy male subjects by adminis...
Detailed Description
Trial A: During trial A the study subject will arrive at the research laboratory and eat a morning meal at 6:30 a.m. corresponding to 5% of the daily energy requirements. It is requested that the stud...
Eligibility Criteria
Inclusion
- Healthy persons (no known disease) without diabetes in the family
- No use of medications
- Non-smokers
- Men
- Age 22-35 years
- Physical activity level (VO2peak) between 30-50 mL O2/min/kg
- BMI between 18.0 and 25.0
Exclusion
- Women
- Physical activity (e.g., running, cycling, fitness, etc.) above 6 hours a week.
- Persons who show signs of metabolic diseases, hematologic diseases, reduced liver function, human immunodeficiency virus (HIV), hepatitis, thyroid diseases or other signs of disease that may affect the outcome of the study or the study subject's wellbeing will be excluded.
- Acute sickness less than 2 weeks prior to study start.
- If disease appears or is identified and/or a need for medication arises after inclusion but before initiation of the study.
- Disease during conclusion of the study
Key Trial Info
Start Date :
February 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2029
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT05233722
Start Date
February 10 2022
End Date
June 1 2029
Last Update
May 16 2024
Active Locations (1)
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1
University of Copenhagen
Copenhagen, Denmark, 2100