Status:

COMPLETED

Effect of Daytime Variation on Postoperative Hyperalgesia Induced by Opioids

Lead Sponsor:

The Second Affiliated Hospital of Chongqing Medical University

Conditions:

Postoperative Hyperalgesia

Eligibility:

All Genders

18-65 years

Brief Summary

To explore the effect of daytime variation on postoperative hyperalgesia induced by opioids. Patients receiving endoscopy surgery under general anesthesia during 08:00-12:00(morning group, n=30) and 1...

Eligibility Criteria

Inclusion

  • American Society of Anesthesiologists classification I-II
  • Abdominal endoscopy surgery
  • Estimated surgery duration 1-2h
  • Right handedness
  • Voluntarily receive postoperative intravenous controlled analgesia

Exclusion

  • Heavy smoking or alcohol dependence
  • Puerpera or lactation women
  • History of chronic pain
  • Analgesic use within one month before surgery
  • Allergy to opioids
  • Can not follow with the study procedure

Key Trial Info

Start Date :

January 12 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 20 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05234697

Start Date

January 12 2022

End Date

May 20 2022

Last Update

December 28 2022

Active Locations (1)

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1

Department of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University

Chongqing, Chongqing Municipality, China, 400010