Status:

COMPLETED

Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients

Lead Sponsor:

University Hospital, Akershus

Conditions:

Pain Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The investigators aim to establish whether the intravenous or the subcutaneous route of administration has clinically significant advantages when parenteral administration of morphine is started with ...

Detailed Description

Intravenous administration has theoretical advantages in more predictable pharmacokinetics and shorter time to maximum effect. Subcutaneous administration is less invasive, requires less specialized p...

Eligibility Criteria

Inclusion

  • Unsatisfactory pain control despite titration of oral or transdermal opioids
  • Planned discharge to home or nursing home

Exclusion

  • Estimated survival time \<2 weeks
  • A clear indication for either intravenous or subcutaneous administration
  • Patient unable to report patient reported outcomes needed in the study due to language barriers or cognitive impairment
  • Impossible to establish venous access

Key Trial Info

Start Date :

March 8 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 31 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05236647

Start Date

March 8 2022

End Date

January 31 2025

Last Update

March 6 2025

Active Locations (1)

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1

Akershus University Hospital

Lørenskog, Norway, 1478