Status:
UNKNOWN
A Prospective Study of UCAD for Diagnosing Benign or Malignant Biliary Obstruction and Follow-up
Lead Sponsor:
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Collaborating Sponsors:
Shanghai Zhongshan Hospital
Ruijin Hospital
Conditions:
Biliary Tract Neoplasms
Pancreatic Carcinoma
Eligibility:
All Genders
18+ years
Brief Summary
Chromosomal instability (CIN) refers to ongoing chromosome segregation errors throughout consecutive cell divisions. CIN is a hallmark of human cancer, and it is associated with poor prognosis, metast...
Detailed Description
CIN results from errors in chromosome segregation during mitosis, leading to structural and numerical chromosomal abnormalities. It will generate genomic heterogeneity that acts as a substrate for nat...
Eligibility Criteria
Inclusion
- Patients diagnosed with malignant biliary obstruction and planned to undergo ERCP(endoscopic retrograde cholangiopancreatography), PTCS(percutaneous transhepatic cholangioscopy) or surgery.
- Malignant biliary obstruction patients confirmed by operation or biopsy.
- Participants without any tumor disease and willing to attend the study.
- Male or female patients aged \>= 18 years.
- Participants signed informed consent form.
Exclusion
- Patients diagnosed with malignant biliary obstruction and planned to undergo ERCP, PTCS or surgery.
- Malignant biliary obstruction patients confirmed by operation or biopsy.
- Participants without any tumor disease and willing to attend the study.
- Male or female patients aged \>= 18 years.
- Participants signed informed consent form.
Key Trial Info
Start Date :
September 3 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2024
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT05237193
Start Date
September 3 2021
End Date
March 1 2024
Last Update
January 17 2023
Active Locations (1)
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1
Xinhua Hospital
Shanghai, Shanghai Municipality, China, 200092