Status:
COMPLETED
The Influence of Tramadol on Platelet Function
Lead Sponsor:
Medical University of Graz
Conditions:
Drug Toxicity
Platelet Dysfunction
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The aim of this ex-vivo study is to quantify the effect of tramadol on platelet aggregation.
Detailed Description
The aim of this study is to quantify the effect of tramadol on platelet aggregation. To this end, the effect of tramadol on platelet function will be demonstrated in an ex-vivo study using optical agg...
Eligibility Criteria
Inclusion
- 18y and older, healthy volunteers
Exclusion
- Age \< 18 years
- Pregnant women
- History of addiction (especially opiate abuse)
- Pre-existing general addictive disease
- Ongoing pain therapy with opiates
- Taking antidepressants (SNRI, SSRI)
- History of thrombocytopathy or coagulation disorders
- Therapy with drugs that influence thrombocyte function (ASS, clopidogrel, prasugrel, ticagrelor or similar)
- Known intolerance to opiates
Key Trial Info
Start Date :
January 26 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 15 2023
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT05237492
Start Date
January 26 2022
End Date
July 15 2023
Last Update
January 18 2024
Active Locations (1)
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1
Dept. of Anaesthesiology and Intensive Care Medicine, Medical University of Graz
Graz, Austria, 8010