Status:
UNKNOWN
Gastro-intestinal Physiology After Anti-Reflux Procedures
Lead Sponsor:
St George's, University of London
Collaborating Sponsors:
Wingate Institute of Neurogastroenterology
Conditions:
Gastroesophageal Reflux
Eligibility:
All Genders
18-90 years
Brief Summary
Gastro-oesophageal reflux disease (GORD) affects 1 in 4 adults and is a condition where stomach acid leaks back up into the oesophagus (gullet). It can cause an uncomfortable burning feeling in the ch...
Detailed Description
GORD is caused by backflow of stomach contents, including acid and bile into the oesophagus. It can lead to distressing symptoms such as heartburn, regurgitation, and chest pain. It is more common in ...
Eligibility Criteria
Inclusion
- Patient under the care of St George's University Hospital NHS Foundation Trust, London
- Decision to specifically undergo Stretta procedure, laparoscopic fundoplication or LINX device (N.B. this study will have no involvement in that decision or choice of procedure)
- Symptoms compatible with GORD, e.g. heartburn, regurgitation, chest pain
- Physiological evidence of GORD, e.g. endoscopy, HRM, pH studies
- Male or Female
- Age 18 to 90
Exclusion
- Patients \< 18 years old or \>90 years old
- Patients with significant medical co-morbidities
- Patients unable to provide consent for study participation
- Patients unable to easily attend hospital for the physiological tests
- Patients who have had complications from their anti-reflux procedure
- Patients who have previously undergone oesophageal surgery
Key Trial Info
Start Date :
May 12 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 20 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05238636
Start Date
May 12 2022
End Date
January 20 2024
Last Update
November 28 2022
Active Locations (1)
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1
St Georges University Hospitals NHS Foundation Trust
London, United Kingdom, SW17 0RE