Status:
COMPLETED
Conventional Fluid Management vs Plethysmographic Variability Index -Based Goal Directed Fluid Management
Lead Sponsor:
Cairo University
Conditions:
Fluid Management During Elective Spine Surgeries
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Plethysmographic variability index is a dynamic method for evaluation of volume status which depends on estimation of respiratory variations in pulse oximeter waveform amplitude. The PVI has been stud...
Detailed Description
This study aims to compare the conventional fluid managment and Plethysmographic Variability index based during elective spine surgeries in prone position. the study hypothesize is: plethysmographic ...
Eligibility Criteria
Inclusion
- • Adult patients (18-65 years)
- ASA I-II
- Patients scheduled for elective lumbar spine surgeries (e.g.: Lumbar fixation and simple discectomy) under general anaesthesia in prone position.
Exclusion
- • Operations which will last for less than 15 minutes. (e.g.: plate and screw adjustment or incomplete terminated surgery)
- Patients with cardiac morbidities e.g. history of unstable angina, impaired contractility with ejection fraction \< 40%, wall motional abnormalities or tight valvular lesions detected by echocardiography, previous cardiac operations or cardiac catherization with stent.
- Patients with heart block and arrhythmia (atrial fibrillation and frequent ventricular or supraventricular premature beat).
- Patient with decompensated respiratory disease (poor functional capacity, generalized wheezes, peripheral O2 saturation \< 90% on room air).
- Patients with peripheral vascular disease or long-standing DM affecting PVI readings.
- Complicated surgeries (huge spine tumors, intraoperative vascular or neurological complications and prolonged durations more than 5 hours) or surgeries with massive blood loss (4 units of packed RBCs in 1 hour or replacement of 50% of total blood volume within 3 hours )
- Pregnancy.
Key Trial Info
Start Date :
January 24 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2022
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT05239286
Start Date
January 24 2022
End Date
September 30 2022
Last Update
October 10 2022
Active Locations (1)
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1
Faculty of Medicine, Kasr Alaini
Cairo, Egypt, 1772