Status:
RECRUITING
Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses
Lead Sponsor:
University of Michigan
Collaborating Sponsors:
National Institute for Biomedical Imaging and Bioengineering (NIBIB)
Conditions:
Lower-limb Orthoses
Frailty/Sarcopenia
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The overall goal of this project is to develop modular, lower-limb, powered orthoses that fit to user-specific weakened joints and control force/torque in a manner that enhances voluntary motion in br...
Detailed Description
The overall goal of this project is to develop modular, lower-limb, powered orthoses that fit to user-specific weakened joints and control force/torque in a manner that enhances voluntary motion in br...
Eligibility Criteria
Inclusion
- Inclusion criteria for able-bodied, young participants will be:
- Aged between 18 to 65 years
- Weigh less than 250 lbs due to limitations in the design of the orthoses
- Ability to lift and lower a 10 kg weight using the neutral-spine squat technique for 10 repetitions
- Exclusion criteria for able-bodied, young adult participants will be:
- Pregnant (self-report)
- Any significant neuromuscular or musculoskeletal disorder that would interfere with the study
- Prior history of chronic lower-back pain
- Unable to walk for 20 minutes
- History of any cardiovascular, vestibular, or visual diseases and/or impairments that may interfere with the study
- Cognitive deficits that would impair their ability to give informed consent or impair their ability to follow simple instructions during the experiments. Cognitive deficits will be determined by a Mini-Mental State Examination (MMSE) score of \<22.
- Adults with a known allergy to medical grade tape
- Inclusion criteria for elderly participants will be:
- Aged between 65 to 85 years
- Weigh less than 250 lbs due to limitations in the design of the orthoses
- Ability to walk 6 minutes without assistance from a person (may use walking aid)
- Exclusion criteria for elderly participants will be:
- Pregnant (self-report)
- Significant pain due to arthritis or other joint problems that would limit their ability to walk
- Any recent lower-extremity fracture (within 3 months)
- Significant neurological (e.g., stroke), orthopedic, or cardiovascular disorder that may affect the ability to walk
- Advised by a physician not to walk or exercise
- Uncontrolled hypertension or diabetes
- Cognitive deficits or visual impairment that would impair their ability to give informed consent or impair their ability to follow simple instructions during the experiments. Cognitive deficits will be determined by a Mini-Mental State Examination (MMSE) score of \<22.
- Adults with a known allergy to medical grade tape
Exclusion
Key Trial Info
Start Date :
July 29 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 21 2026
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT05240014
Start Date
July 29 2022
End Date
September 21 2026
Last Update
July 18 2025
Active Locations (1)
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1
Rehab Lab, University of Michigan
Ann Arbor, Michigan, United States, 48109