Status:
RECRUITING
Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients with Bipolar Depression
Lead Sponsor:
The University of Texas Health Science Center, Houston
Collaborating Sponsors:
Milken Institute
Conditions:
Anhedonia
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate whether transcranial direct-current stimulation (tDCS) will engage reward-related brain circuitry, more specifically the uncinate fasciculus (UF) tract, whi...
Eligibility Criteria
Inclusion
- diagnosis of Bipolar Disorder and clinically significant anhedonia
- mild symptoms of depression
Exclusion
- substance abuse/dependence and any use of drugs (except alcohol or nicotine) in the previous month of the baseline assessment
- participants with personality disorder that would interfere with study participation according to clinical judgment
- previous neurological conditions (epilepsy, traumatic brain injury, stroke, etc)
- any severe, life-threatening non-psychiatric medical condition
- specific contraindications for tDCS (metallic plates in the head)
- Participants identified as acutely suicidal or severely agitated
Key Trial Info
Start Date :
October 6 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT05240352
Start Date
October 6 2022
End Date
December 1 2026
Last Update
February 14 2025
Active Locations (1)
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1
The University of Texas Health Science Center at Houston
Houston, Texas, United States, 77030