Status:
COMPLETED
Macrophage Markers in Periodontal and Peri-implant Health and Disease
Lead Sponsor:
Biruni University
Collaborating Sponsors:
University of Turku
Conditions:
Peri-Implantitis
Periodontitis
Eligibility:
All Genders
18+ years
Brief Summary
Macrophage surface markers (CD80, CD163 and CD206) will be evaluated in periodontally healthy gingiva, healthy peri-implant mucosa, and periodontitis and peri-implantitis lesions.
Detailed Description
Soft tissue biopsies obtained from clinically healthy gingiva, healthy peri-implant mucosa, Stage III Grade C periodontitis lesions and peri-implantitis lesions will be evaluated. Healthy peri-implan...
Eligibility Criteria
Inclusion
- diagnosed with generalized Grade C Stage III periodontitis
- diagnosed with peri-implantitis
- periodontally healthy individuals with dental implants in the primary healing period
- periodontally healthy individuals who are in need of crown lengthening / gingivectomy or extraction
Exclusion
- systemic disease
- smoking / former smokers
- regular medicine intake
- antibiotic or anti-inflammatory medicine intake in the last 3 months
- pregnancy or lactation
Key Trial Info
Start Date :
March 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2021
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT05242354
Start Date
March 1 2021
End Date
December 31 2021
Last Update
May 18 2023
Active Locations (1)
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1
Biruni University
Istanbul, Turkey (Türkiye)