Status:
COMPLETED
Effect of Low-volume (1L) vs Intermediate-volume (2L) Bowel Preparation on Cost-effectiveness and Quality of Life
Lead Sponsor:
Radboud University Medical Center
Conditions:
Colorectal Cancer
Colonic Polyp
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Adequate bowel preparation for colonoscopy is paramount for optimal diagnostic accuracy and safety. However, the need for high volumes to clean the colon often makes it difficult for patients to adher...
Detailed Description
Background and aims: Adequate bowel preparation for colonoscopy is paramount for optimal diagnostic accuracy and safety. However, the need for high volumes to clean the colon often makes it difficult ...
Eligibility Criteria
Inclusion
- Age \> 18 years
- Planned elective colonoscopy for surveillance or diagnostic indications
Exclusion
- Therapeutic colonoscopy (e.g. endoscopic mucosal resection (EMR)
- History of (sub) total colectomy
- Inflammatory bowel disease (IBD)
- Inpatient status
- Indication for an intensified bowel preparation regime
- Emergency colonoscopy
- Limited Dutch language skills
- Dementia
- Visual impairment
- Commonly accepted contra-indications for non-iso osmotic bowel preparation and ascorbate:
- Glucose-6-phosphate-dehydrogenase (G6PD) deficiency
- (sub)ileus
- Bowel obstruction or perforation
- Acute abdomen
- Gastroparesis
- intolerance for any of the formulation ingredients
- Severe renal insufficiency (creatinine clearance \< 30mL/min)
- Congestive heart failure (NYHA III or IV)
- Phenylketonuria
Key Trial Info
Start Date :
May 16 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 2 2023
Estimated Enrollment :
509 Patients enrolled
Trial Details
Trial ID
NCT05242562
Start Date
May 16 2022
End Date
March 2 2023
Last Update
November 21 2024
Active Locations (1)
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1
Radboud university medical center
Nijmegen, Gelderland, Netherlands, 6525GA