Status:
UNKNOWN
Characterization of Retinal Microvascular and FAZ Changes in Ischemic Stroke and Its Different Types
Lead Sponsor:
Peking University Third Hospital
Conditions:
Ischemic Stroke
Eligibility:
All Genders
40-80 years
Brief Summary
The study aimed to access the microvascular changes in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) in patients with ischemic stroke and its different types using optical coh...
Detailed Description
Investigators used OCTA to quantitatively access the retinal microvasculature of SCP and DCP, aiming to detect the geometry changes of retinal microvasculature and FAZ in ischemic stroke patients and ...
Eligibility Criteria
Inclusion
- Patients who were diagnosed with ischemic stroke by MRI were scheduled for an OCTA examination. The diagnosis of ischemic stroke was obtained from previous diagnostic reports or electronic medical records, according to the diagnostic criteria from the Trial of Org 10172 in Acute Stroke Treatment (TOAST).
Exclusion
- 1\) Retinal diseases or diseases affecting vessel structure in fundus photography, including age-related maculopathy; diabetic retinopathy, central serous chorioretinopathy, retinal pigment epithelial detachment and glaucoma); poor cooperation in ophthalmic examinations; high refractive error (\>+6.00 D or \<-6.00 D Spherical Equivalent); low-quality OCTA images (signal strength index \< 6/10). Inclusion criteria for healthy controls were no history of ischemic stroke or other neurological and ocular diseases.
Key Trial Info
Start Date :
January 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05243849
Start Date
January 1 2022
End Date
June 1 2022
Last Update
February 17 2022
Active Locations (1)
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1
Peking University Third Hospital
Beijing, China