Status:

TERMINATED

Blood Flow Restriction Training in ACL Surgery

Lead Sponsor:

University of Arkansas

Conditions:

Anterior Cruciate Ligament Injuries

Eligibility:

All Genders

18-34 years

Phase:

NA

Brief Summary

This will be a randomized pilot study to determine the effectiveness of Personalized Blood Flow Restriction (PBFR) technique in conjunction with prescribed physical therapy (PT) in a cohort of anterio...

Detailed Description

This will be a randomized pilot study to determine the effectiveness of Personalized Blood Flow Restriction (PBFR) technique in conjunction with prescribed physical therapy (PT) in a cohort of anterio...

Eligibility Criteria

Inclusion

  • Men and women, ages 18-34 years.
  • Scheduled to undergo elective ACL surgery at UAMS.
  • Capable of providing informed consent.
  • Willing to exercise with BFR.
  • COVID-19 negative or asymptomatic.

Exclusion

  • Any surgical indication other than ACL repair.
  • Body mass index \>40.
  • Pregnant female.
  • Neurological, musculoskeletal, or other disorder that would preclude them from completing the exercise training intervention and all performance tests.
  • Hypertension as evidenced by systolic BP \>150 at rest OR diastolic BP \>85 at rest.
  • Heart failure as evidenced by use of prescription diuretics.
  • History of atrial fibrillation.
  • Oxygen saturation \<95% on room air at rest.
  • Any other medical condition that would interfere with testing or increase one's risk of complications during exercise.
  • Currently receiving androgen (e.g., testosterone) or anabolic (e.g., GH, IGF-I) therapy.
  • Compromised vascular circulation in the legs (e.g. peripheral vascular disease).
  • History of deep vein thrombosis.
  • Varicose veins in the legs.
  • Known Sickle cell disease or trait.
  • Unwilling to avoid using protein or amino-acid supplements during participation.
  • Unwilling to avoid using BFR during prescribed post-operative physical therapy.

Key Trial Info

Start Date :

April 18 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 30 2023

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT05245864

Start Date

April 18 2022

End Date

January 30 2023

Last Update

October 9 2024

Active Locations (1)

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UAMS Center on Aging

Little Rock, Arkansas, United States, 72205