Status:

ACTIVE_NOT_RECRUITING

Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer

Lead Sponsor:

Xiangyun Zong

Conditions:

Breast Cancer Lymphedema

Eligibility:

All Genders

18-69 years

Brief Summary

The purpose of this study is to compare the difference in the incidence of upper limb edema and dysfunction between the Preponderant lymphatic reflux group (high ratio of axillary lymphatic reflux to ...

Eligibility Criteria

Inclusion

  • Age 18-69 years old,
  • Regardless of gender,
  • Breast masses were diagnosed by histology and pathology, stage II -III.
  • Clinical palpation of axillary lymph nodes is positive, or
  • Axillary lymph node puncture pathology is positive, or
  • The multidisciplinary treatment cooperation group (MDT) recommends axillary lymph node dissection,
  • Good physical state score (0-1),
  • No severe organ complications,
  • No congenital or acquired diseases affecting the normal morphology and functional activities of the upper limbs,
  • Informed consent, understanding and compliance with research requirements.

Exclusion

  • Pregnancy or lactation,
  • Inflammatory breast cancer,
  • Clinical findings of metastatic lesions,
  • Sentinel lymph node biopsy was negative,
  • History of upper limb or shoulder, chest, back trauma or surgery,
  • Previous history of local radiotherapy,
  • History of other tumors,
  • Vascular embolic disease,
  • Those who are unable to comply with the clinical trial requirements for any reason.

Key Trial Info

Start Date :

January 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2029

Estimated Enrollment :

258 Patients enrolled

Trial Details

Trial ID

NCT05246592

Start Date

January 1 2022

End Date

April 1 2029

Last Update

September 19 2024

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China, 200233

2

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China, 310022

3

Shanghai Fengxian Central Hospital

Shanghai, China, 201499