Status:
UNKNOWN
Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo Measurements
Lead Sponsor:
University Medical Center Groningen
Collaborating Sponsors:
Technical University of Munich
Universidad Carlos III de Madrid
Conditions:
Esophageal Adenocarcinoma
Barrett Esophagus
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The investigators hypothesize that detection of field cancerization in the GI tract could be performed during endoscopy by performing Raman and scattering measurements. Together with the Technical Uni...
Detailed Description
Esophageal adenocarcinoma and colorectal carcinoma are common conditions that are responsible for high mortality rates among the worldwide population. Respectively, patients with Barrett's esophagus a...
Eligibility Criteria
Inclusion
- Scheduled for either a gastroscopy in the context of a Barrett's esophagus or a colonoscopy in the context of colorectal polyps;
- Age of 18 years or older;
- Written informed consent.
Exclusion
- Patients with simultaneous neoplasia elsewhere in the GI tract;
- Patients with a medical history of head and neck or lung cancer;
- Patients with a history of endoluminal ablative therapy or radiation therapy;
- Patients younger than 18 years
- Other medical conditions of the esophagus or colon that potentially can disturb measurements of the SRS/scattering spectra such as (eosinophil) esophagitis, inflammatory bowel disease or a medical history of radiation therapy;
- Physical or mental disorders that comprise the ability of the patient to give informed consent.
Key Trial Info
Start Date :
July 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05247346
Start Date
July 1 2022
End Date
December 1 2024
Last Update
June 13 2023
Active Locations (1)
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1
University Medical Center Groningen
Groningen, Netherlands, 9713 GZ