Status:

COMPLETED

Clinical Effectiveness and Safety of a Novel Oral Rehydration Solution

Lead Sponsor:

Mead Johnson Nutrition

Conditions:

Gastroenteritis Acute

Eligibility:

All Genders

1-5 years

Phase:

NA

Brief Summary

This is a randomised, controlled, open-label study to determine the clinical effectiveness and safety of a novel ORS compared with a commercial ORS in children 1 to 5 years of age attending emergency ...

Eligibility Criteria

Inclusion

  • 1 to 5 years of age, inclusive at randomization
  • Hospitalized with mild to moderate dehydration due to ongoing diarrhea
  • Signed informed consent obtained for child's participation in the study

Exclusion

  • Severe dehydration and/or use of IV fluids for current hospitalization
  • Experiencing bloody diarrhea or diarrhea due to Cholera, Dysentery, persistent/chronic diarrhea, diarrhea with severe malnutrition, diarrhea associated with recent antibiotic use
  • In the opinion of the Investigator, not suitable for treatment with ORS
  • Have any underlying disease or disorder that may, in the opinion of the Investigator, affect the results of the study if they were enrolled (includes, but is not limited to, gastrointestinal disorders such as Crohn's disease or other inflammatory bowel disease or congenital malabsorption disorders)
  • Cause of the dehydration is something other than diarrhea
  • Known to be allergic to any of the components of the Investigational ORS

Key Trial Info

Start Date :

June 30 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 18 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05247879

Start Date

June 30 2022

End Date

January 18 2024

Last Update

March 25 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Ramathibodi Hospital

Bangkok, Thailand

2

Siriraj Hospital

Bangkok, Thailand

3

Maharaj Nakorn Chiang Mai Hospital

Chiang Mai, Thailand

4

Naresuan University Hospital

Phitsanulok, Thailand