Status:
COMPLETED
Dosing of Ketorolac Impacts Post-cesarean paiN manaGemenet (KING)
Lead Sponsor:
Ohio State University
Conditions:
Post Cesarean Pain
Eligibility:
FEMALE
18-45 years
Brief Summary
This is a randomized controlled single blinded trial to compare the morphine milligram equivalents (MME) use in the first 24 hours postoperatively after cesarean section in patients receiving a single...
Detailed Description
Administration of a dose of ketorolac for postoperative pain management at end of cesarean is routine practice at our institution. This is a randomized controlled single blinded trial at The Ohio Sta...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Pregnant individuals aged 18-45 with a viable single or twin intrauterine pregnancy
- Cesarean section as the delivery mode
- Regional anesthesia (Spinal, Epidural, Combined Spinal Epidural)
- Exclusion criteria:
- Known allergy or adverse reaction to Non-steroidal anti-inflammatory drugs (NSAIDs), aspirin, or ketorolac
- Patients with peptic ulcer disease, preexisting kidney or liver disease
- Hemodynamically unstable due to hemorrhage
- Acute or chronic pain disorder
- Physician/provider or patient refusal
- Estimated blood loss \> 2000 mL
- General anesthesia
- Opioid use disorder
- Emergent Cesarean delivery
- Coagulation disorders
- Active asthma
- Patients weighing \<50 kg
Exclusion
Key Trial Info
Start Date :
June 8 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 30 2023
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT05248984
Start Date
June 8 2022
End Date
November 30 2023
Last Update
January 5 2024
Active Locations (1)
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1
The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine
Columbus, Ohio, United States, 43210