Status:
COMPLETED
Characterization of Bovine Adrenal Medulla as a New Surrogate Model of Non-histaminergic Itch
Lead Sponsor:
Aalborg University
Conditions:
Itch
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
With this experiment, the experimenter wish evaluate the role of TRPA1 on non-histaminergic itch induced by BAM8-22
Detailed Description
With this experiment, the experimenter wish evaluate the role of TRPA1 on non-histaminergic itch induced by BAM8-22 2 (Bovine Adrenal Medulla), which is found naturally in the human body and which has...
Eligibility Criteria
Inclusion
- Healthy men and women
- 18-60 years
- Speak and understand English
Exclusion
- Pregnancy or lactation
- Drug addiction defined as any use of cannabis, opioids or other drugs
- Previous or current history of neurological, dermatological, immunological musculoskeletal, cardiac disorder or mental illnesses that may affect the results (e.g. neuropathy, muscular pain in the upper extremities, etc.)
- Moles, wounds, scars or tattoos in the area to be treated or tested
- Lack of ability to cooperate •
- Current use of medications that may affect the trial such as antihistamines and pain killers.
- Skin diseases
- Consumption of alcohol or painkillers 24 hours before the study days and between these - Acute or chronic pain •
- Participation in other trials within 1 week of study entry (4 weeks in the case of pharmaceutical trials)
Key Trial Info
Start Date :
February 11 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2022
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT05249387
Start Date
February 11 2022
End Date
October 30 2022
Last Update
September 28 2023
Active Locations (1)
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1
Giulia Erica Aliotta
Aalborg, Denmark, 9000