Status:

WITHDRAWN

Statin InTensity to Prevent Coronary Artery Vasculopathy After Heart Transplantation

Lead Sponsor:

Montefiore Medical Center

Conditions:

Vasculopathy

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The investigator's propose to conduct an open-label randomized controlled trial to determine if higher intensity statin (HS) can reduce CAV in comparison to lower intensity statin (LS) after HT. All c...

Detailed Description

Outcomes after heart transplantation (HT) are limited by development of coronary allograft vasculopathy (CAV). CAV comprises of macro- and microvascular coronary disease and is the third leading cause...

Eligibility Criteria

Inclusion

  • Waitlisted for Heart Transplantation
  • Capacity to provide informed consent

Exclusion

  • History of statin allergy or intolerance
  • Hepatic dysfunction
  • Redo Heart Transplant
  • Awaiting combined heart and liver transplantation

Key Trial Info

Start Date :

January 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2030

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT05251129

Start Date

January 1 2025

End Date

June 1 2030

Last Update

January 13 2025

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