Status:
UNKNOWN
A Combined Model Based on Spleen Stiffness, Liver Stiffness and Platelets for Assessing Portal Hypertension in Compensated Cirrhosis (CHESS2202)
Lead Sponsor:
Hepatopancreatobiliary Surgery Institute of Gansu Province
Collaborating Sponsors:
LanZhou University
Shulan (Hangzhou) Hospital
Conditions:
Portal Hypertension
Eligibility:
All Genders
18+ years
Brief Summary
Portal hypertension contributed to the main complications of liver cirrhosis. Currently, hepatic venous pressure gradient (HVPG) was the reference standard for evaluating portal pressure in patients w...
Detailed Description
Portal hypertension contributed to the main complications of liver cirrhosis. Currently, hepatic venous pressure gradient (HVPG) was the reference standard for evaluating portal pressure in patients w...
Eligibility Criteria
Inclusion
- age above or equal to 18-year-old
- fulfilled diagnosis of compensated cirrhosis based on radiological, histological features of liver cirrhosis and clinical manifestations
- without decompensated events (e.g. ascites, bleeding, or overt encephalopathy)
- with spleen stiffness and liver stiffness by a dedicated probe on transient elastography examination and platelet count measurement
- with HVPG measurement
- signed informed consent
Exclusion
- non-cirrhotic portal hypertension
- accepted primary prevention (non-selective beta blockers or endoscopic variceal ligation)
- lactation or pregnancy
- suspicious or confirmed hepatocellular carcinoma
- asplenia or splenectomy
- incomplete clinical information
Key Trial Info
Start Date :
September 28 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 27 2024
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05251272
Start Date
September 28 2021
End Date
September 27 2024
Last Update
April 25 2023
Active Locations (5)
Enter a location and click search to find clinical trials sorted by distance.
1
The First Hospital of Lanzhou University
Lanzhou, Gansu, China, 730000
2
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Nanjing, Jiangsu, China, 210000
3
Qufu People's Hospital
Jining, Shandong, China, 272000
4
The Third People's Hospital of Taiyuan
Taiyuan, Shanxi, China, 030000