Status:

UNKNOWN

A Clinical Study on the Effects of Inhalation of Volatile Oil of Cang-Ai Via the Nose on Patients With Depression

Lead Sponsor:

Jieqiong Cui

Conditions:

Depressive Disorder

Mental Disorder in Adolescence

Eligibility:

All Genders

6-28 years

Phase:

EARLY_PHASE1

Brief Summary

In this study, 60 depressed patients who meet the criteria will randomly be divided into a test group and a control group, with 30 patients in each group. The test group will be given Volatile oil of ...

Detailed Description

Depression is a common psychiatric disorder characterised by persistent depressed mood, loss of interest and feelings of helplessness. Depression has the highest burden of illness of any mental illnes...

Eligibility Criteria

Inclusion

  • Meeting the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnostic criteria for depressive episodes.
  • Beck Depression Scale \>10; 24-item Hamilton Depression Scale (HAMD) score \>20
  • Healthy sense of smell, no allergic diseases, respiratory diseases, age 16-40 years, male or female.
  • No use of antidepressants and other psychiatric drugs or physiotherapy such as electroconvulsive shock or transcranial magnetic stimulation (TMS) for at least 1 week prior to the intervention ⑤All subjects volunteered to participate and signed an informed consent form after approval by the hospital's ethics committee

Exclusion

  • History of schizophrenia, alcohol and drug dependence strictly excluded ②Depression with a history of organic brain disease and endocrine disorders or secondary to other psychiatric disorders
  • Score \>3 on the Hamilton Depression Inventory for Suicide ④Pregnant and breastfeeding women with a history of manic or hypomanic episodes ⑤Family history of monophasic or bipolar disorder

Key Trial Info

Start Date :

November 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05251779

Start Date

November 1 2022

End Date

December 1 2022

Last Update

October 20 2022

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A Clinical Study on the Effects of Inhalation of Volatile Oil of Cang-Ai Via the Nose on Patients With Depression | DecenTrialz