Status:

UNKNOWN

Macular Pigment Optical Density in Primary Angle-closure Disease

Lead Sponsor:

Zhongshan Ophthalmic Center, Sun Yat-sen University

Conditions:

Glaucoma

Glaucoma, Angle-Closure

Eligibility:

All Genders

40-90 years

Brief Summary

Glaucoma is the leading cause of irreversible blindness in the world, and primary angle-closure glaucoma (PACG) is the most important type of glaucoma in Asia. Primary angle closure disease (PACD) is ...

Detailed Description

Observation index: Visual acuity,Intraocular pressure,Ophthalmoscope,MPOD,Visual field and OCT. Inspection parameters of OCT: 1. Retinal nerve fiber layer thickness 2. Ganglion cell complex thicknes...

Eligibility Criteria

Inclusion

  • Experimental group:
  • (1) According to the diagnostic criteria of PACD
  • (2)History of peripheral iridectomy or trabeculectomy
  • (3)Over 40
  • (4)Phakic eyes
  • (5)Intraocular pressure is less than 21mmhg, more than one week
  • (6)Eyes with clear optical media.
  • Control group:
  • (1)No history of glaucoma and other eye diseases
  • (2)Phakic eyes
  • (3)Over 40
  • (4)Intraocular pressure10\~21mmHg

Exclusion

  • (1)History of corneal diseases
  • (2)History of eye tumor or other ophthalmic surgery
  • (3)Cataract
  • (4)Taking supplements containing lutein within 6 months
  • (5)Snellen's visual acuity was less than 6 / 20,the diopter is beyond ± 6 degrees

Key Trial Info

Start Date :

November 11 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 30 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05251792

Start Date

November 11 2021

End Date

December 30 2024

Last Update

February 13 2023

Active Locations (1)

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1

Zhognshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China, 510060