Status:

COMPLETED

The Impact of Broad Bean Hull on Blood Glucose Control and Gut Health

Lead Sponsor:

University of Aberdeen

Conditions:

Healthy

Overweight

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

This study aims to assess the effects of broad bean hull (BBH) consumption on blood glucose and gut health. Broad bean (Vicia faba) is widely cultivated in Scotland, with the UK being the most signifi...

Detailed Description

The study aims to confirm in vivo the effects of consuming broad bean hull on blood glucose control and gut health. Although in vitro evidence is promising, its benefits remain confirmed in vivo in hu...

Eligibility Criteria

Inclusion

  • Healthy males and females
  • Aged 18-75 years old.
  • BMI 23-35 kg/m2
  • HbA1c \<6.5%
  • Total cholesterol ≤ 7 mmol/l

Exclusion

  • Glucose 6 Phosphate Dehydrogenase deficiency
  • Diagnosed for chronic diseases; thyroid disorders, metabolic/genetic diseases, diabetes and disorders of glycaemic control; cardiovascular disease; irritable and inflammatory bowel disorders.
  • Women with polycystic ovaries syndrome (PCOS)
  • Women who are lactating or breastfeeding, pregnant
  • On prescription medications known to affect metabolism, including hormonal contraceptives and thyroid medications, and hormonal replacement therapy
  • Have taken a course of antibiotics in the past four weeks
  • Allergic/intolerant to foods provided in the study
  • Diagnosed for high blood pressure and on prescription medications such as Ramipril
  • Alcohol and/or other substance abuse
  • Smoking and the use of e-cigarettes, nicotine patches and nicotine gums
  • Physically active at a competitive level
  • Usually not consuming significantly more than five portions of fruits and vegetables per day
  • Poor venous access

Key Trial Info

Start Date :

January 31 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 31 2020

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT05252013

Start Date

January 31 2019

End Date

March 31 2020

Last Update

February 23 2022

Active Locations (1)

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University of Aberdeen, Rowett Institute

Aberdeen, Aberdeen City, United Kingdom, AB10 6JW