Status:

UNKNOWN

Quantitative mpMRI to Predict Metastatic Potential of Prostate Cancer

Lead Sponsor:

Radboud University Medical Center

Conditions:

Prostate Cancer

Eligibility:

MALE

50+ years

Brief Summary

The primary aim of this study is to assess the potential of quantitative MRI measurements to predict localized prostate cancer T-stage and disease spread to nodes (N-stage) by correlating quantitative...

Detailed Description

Patients diagnosed with prostate cancer will likely not die from the primary tumor, but from (extended) metastatic disease. One of the first steps towards extended metastatic disease is the presence o...

Eligibility Criteria

Inclusion

  • Histologically proven primary cancer of the prostate, based on prostate biopsy-core analysis.
  • Patient is scheduled and fit for PSMA-PET/CT
  • Age≥50 years. Ability to give voluntary written informed consent to participate in this study.

Exclusion

  • Contraindication for MRI-scanning, i.e. claustrophobia, intracranial metal clips, metallic bodies in the eye, implanted electric and electronic devices not eligible for MRI (pacemakers, insulin pumps, cochlear implants, neurostimulators).
  • Prior prostate cancer treatment.
  • Prior pelvic surgery, associated with pelvic lymphadenopathy
  • Presence of any medical condition that in the opinion of the investigator/treating physician will affect patients' clinical status by participating in this trial.
  • Inability to lie still for 45 minutes or comply with imaging.
  • The patient is already enrolled in one or more concurrent studies, which could confound the results of this study, according to the investigators.

Key Trial Info

Start Date :

July 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2023

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05252806

Start Date

July 1 2022

End Date

March 1 2023

Last Update

June 22 2022

Active Locations (1)

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Radboud university medical centre

Nijmegen, Netherlands