Status:

ENROLLING_BY_INVITATION

Infective Endocarditis Surgery Using Conventional Prosthetic Valves Versus Cryopreserved Aortic Homograft

Lead Sponsor:

Centre Cardiologique du Nord

Collaborating Sponsors:

Campus Bio-Medico University

Henri Mondor University Hospital

Conditions:

Infective Endocarditis

Heart Failure

Eligibility:

All Genders

18-90 years

Brief Summary

: Evidence suggested that autologous or allogeneic tissue is more suitable to synthetic material in an infected field. Given the unwillingness of some surgeons to use artificial foreign materials, suc...

Detailed Description

The target population enrolled in the study includes patients with aortic-valve endocarditis at risk of embolization, heart failure and uncontrolled infection undergoing AVR with the use of CAH or con...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Duke Criteria
  • Uncontrolled Infection Local abscess Large vegetation False aneurysm, Fistula, Dehiscence of PV
  • Embolism Large vegetation \>10mm, persistent infection
  • Heart Failure Involvement of aortic root, intervalvular fibrosa, pulmonary edema, cardiogenic shock
  • Exclusion Criteria :
  • Pediatric
  • Any echocardiographic evidence of absence of IE

Exclusion

    Key Trial Info

    Start Date :

    January 1 2005

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2026

    Estimated Enrollment :

    760 Patients enrolled

    Trial Details

    Trial ID

    NCT05253469

    Start Date

    January 1 2005

    End Date

    December 1 2026

    Last Update

    July 1 2025

    Active Locations (1)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 1 (1 locations)

    1

    Francesco Nappi

    Saint-Denis, France, 93200

    Infective Endocarditis Surgery Using Conventional Prosthetic Valves Versus Cryopreserved Aortic Homograft | DecenTrialz