Status:

RECRUITING

Precision Medicine Randomized Clinical Trial Comparing Molecular Tumor Board Assisted Care to Usual Care

Lead Sponsor:

Timothy Mullett

Collaborating Sponsors:

Eli Lilly and Company

Conditions:

Non-Small Cell Lung Cancer

Eligibility:

All Genders

18-120 years

Phase:

NA

Brief Summary

This trial will compare Molecular Tumor Board (MTB) assisted care to usual care for patients who have newly diagnosed histologically or cytologically confirmed stage IIb-IV Non-Small Cell Lung Cancer ...

Eligibility Criteria

Inclusion

  • Clinically suspected or histologically confirmed stage IIb-IV NSCLC who are planning to undergo treatment
  • No prior systemic therapies for NSCLC, with the exception of adjuvant therapy for early stage NSCLC. Prior surgery and/or radiation is allowed.
  • Ability to understand and the willingness to sign a written informed consent document.

Exclusion

  • Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with targeted therapy, in the opinion of the treating physician.
  • Pregnancy

Key Trial Info

Start Date :

April 13 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2036

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT05254795

Start Date

April 13 2022

End Date

December 1 2036

Last Update

August 6 2025

Active Locations (1)

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University of Kentucky

Lexington, Kentucky, United States, 40506