Status:

COMPLETED

Effectiveness of Nano-silver Fluoride and Silver Diamine Fluoride for Arresting Early Childhood Caries

Lead Sponsor:

Alexandria University

Conditions:

Early Childhood Caries

Eligibility:

All Genders

2-4 years

Phase:

NA

Brief Summary

Aim of the study: To evaluate and compare the clinical cariostatic efficacy of NSF with 38% SDF solution after sex and twelve months in arresting ECC lesions. The Null hypothesis will be that no stat...

Eligibility Criteria

Inclusion

  • Children younger than 4 years old.
  • The presence of at least one active carious lesion on a primary tooth, with scores 3 and higher (according to the International Detection and Assessment System- ICDAS II)
  • Completion of an informed consent to participate in the study.

Exclusion

  • Children reporting spontaneous or elicited pain from caries or showing any signs of pulpal infection, swelling and/or abscess, obvious discoloration of the tooth and premature hypermobility.
  • Parental refusal to participate in the study.
  • Allergy or sensitivity to silver or any of the materials included in the study.

Key Trial Info

Start Date :

March 15 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 3 2023

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT05255913

Start Date

March 15 2022

End Date

August 3 2023

Last Update

September 26 2023

Active Locations (1)

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1

Faculty of Dentistry

Alexandria, Egypt