Status:
COMPLETED
Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia
Lead Sponsor:
University of Missouri-Columbia
Collaborating Sponsors:
American Heart Association
Conditions:
Vasodilation
Hypoxia
Eligibility:
All Genders
18-45 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this project is to identify sex-related differences in the effect of hypoxia on sympathetic vascular transduction.
Eligibility Criteria
Inclusion
- healthy adult men and women;
- 18-45 years of age;
- BMI 18-30 kg/m2;
- non-pregnant/non-breastfeeding;
- non-nicotine users;
Exclusion
- Pregnancy, breastfeeding, hormonal contraceptives
- Diagnosed sleep apnea
- Current smoking/Nicotine use/drug use
- Nerve/neurologic disease
- Cardiovascular, hepatic, renal, respiratory disease
- Blood pressure ≥140/90 mmHg
- Diabetes, Polycystic ovarian syndrome
- Communication barriers
- Prescription medications
- Recent COVID-19 diagnosis with symptoms
Key Trial Info
Start Date :
April 26 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2025
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT05256069
Start Date
April 26 2023
End Date
July 31 2025
Last Update
September 15 2025
Active Locations (1)
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1
University of Missouri-Columbia
Columbia, Missouri, United States, 65211