Status:

UNKNOWN

Clinical Decision Biological Biomarker and Prognosis Prediction of Hepatocellular Carcinoma by Deep Learning

Lead Sponsor:

Ping Liang

Conditions:

Hepatocellular Carcinoma

Contrast-enhanced Ultrasound

Eligibility:

All Genders

18+ years

Brief Summary

Developing a deep learning model based on contrast-enhanced ultrasound (CEUS) to predict the prognosis of hepatocellular carcinoma (HCC) and aid choose operation decisions

Detailed Description

Collecting CEUS and clinical data of HCC from different institutions retrospectively. Developing a deep learning model based on CEUS to predict the prognosis of HCC. Developing a deep learning model ...

Eligibility Criteria

Inclusion

  • patients with HCC (Ia, Ib, IIa stage) China liver cancer staging who underwent resection or ablation
  • without macro-vascular invasion
  • Child-Pugh A/B grade
  • HCC is proved by pathological examination or two enhanced imaging
  • CEUS (Sonovue or Sonozoid) images are performed two weeks before the operation
  • Invasive biomarker or prognosis of HCC available
  • CEUS images are included in at least three stages (Arterial phase, Portal phase, and Late phase)

Exclusion

  • postop follow-up loss or expired less than 3 months
  • patients with co-malignancy
  • poor images quality for analyzing

Key Trial Info

Start Date :

January 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT05257694

Start Date

January 1 2022

End Date

December 31 2025

Last Update

October 21 2022

Active Locations (1)

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1

Chinese PLA General Hospital

Beijing, Beijing Municipality, China, 100853