Status:
TERMINATED
Use of Neurostimulation As a Tool for Reconditioning the Neuromuscular System of Patients Admitted to the ICU for Septic Shock
Lead Sponsor:
Centre Hospitalier Universitaire Dijon
Conditions:
Septic Shock
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Patients hospitalized in the ICU are likely to develop sarcopenia due to a progressive and generalized decrease in muscle mass that is responsible for generalized muscle weakness known as resuscitatio...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Admitted to the ICU for :
- Sepsis as defined by the presence of an infection, of known or suspected origin + organ dysfunction with a SOFA score ≥ 2
- Or septic shock defined by sepsis with persistent hypotension requiring vasopressors to maintain mean artérial blood pressure ≥ 65 mmHg and serum lactate level \> 2 mmol/l despite adequate vascular filling
- After obtaining informed consent from a relative/trusted person or patient included in an emergency situation
- Patient affiliated to national health insurance.
Exclusion
- Patient with a contraindication to the application of ES (e.g. pacemaker, defibrillator)
- Patient with a diagnosis of deep vein thrombosis and/or pulmonary embolism, confirmed and treated within the last 48 hours
- Patient with cardiac arrest prior to study inclusion
- Patient for whom a decision to limit or stop treatment has been made by the medical team
- Patients with a very poor prognosis in the very short term due to major co-morbidities (Child Pugh score C cirrhosis, terminal cancer, neuro-evolutionary disease with no treatment plan...)
- Patients with known neuro-orthopaedic and sensory disorders prior to inclusion, whether of originating in the spinal cord, nerve or brain.
- Person subject to a legal protection measure (curatorship, guardianship)
- Pregnant, parturient or breastfeeding women.
- Secondary
Key Trial Info
Start Date :
March 25 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 11 2024
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT05257759
Start Date
March 25 2022
End Date
June 11 2024
Last Update
February 19 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Chu Dijon Bourgogne
Dijon, France