Status:

WITHDRAWN

Immediate Effects of DLPFC tDCS on Attention Bias

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

New York University

Conditions:

Depression

Eligibility:

FEMALE

18-45 years

Phase:

NA

Brief Summary

This research is being done to test if the investigators can modify or reduce negative attention bias in depression following a single session of transcranial direct current stimulation (tDCS) over th...

Detailed Description

This prospective pilot study will recruit 25 female participants, ages 18-45 (inclusive), with mild to severe depression (based on BDI-II score range 14-19 for mild and 29-63 for severe) to determine ...

Eligibility Criteria

Inclusion

  • Aged 18-45
  • Female
  • Mild to severe depression (determined by BDI-II scores of 14-19 and 29-63, respectively)
  • If taking antidepressants, medication must be stable ≥ 30 days prior to screening

Exclusion

  • Wide-Range Achievement Test-Fourth Edition (WRAT-4) Reading Subtest standard score \<85 (to ensure understanding of test procedures)
  • Insufficient visual and motor ability to operate the intervention and assessments as judged by treating neurologist or study staff
  • Primary psychiatric disorder other than depression (based on MINI)
  • Primary neurologic condition that would prevent ability to participate (as determined by study clinician).
  • History of head trauma in the last year
  • Medical device implants in the head or neck
  • History or current uncontrolled seizure disorder
  • Current substance abuse disorder
  • Pregnant or lactating women
  • Skin disorder/sensitive skin near stimulation locations

Key Trial Info

Start Date :

March 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2023

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT05263440

Start Date

March 1 2023

End Date

June 30 2023

Last Update

February 5 2025

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