Status:
COMPLETED
The Acute Effects of Meals Rich in Saturated or Unsaturated Fatty Acids on Postprandial Lipaemia in Healthy Men
Lead Sponsor:
University of Reading
Conditions:
Cardiovascular Risk Factor
Eligibility:
MALE
30-70 years
Phase:
NA
Brief Summary
Current dietary recommendations suggest that lowering intake of saturated fats or replacing it with unsaturated fats will decrease the risk of developing cardiovascular disease. Coconut oil has gained...
Eligibility Criteria
Inclusion
- Healthy men
- Aged between 30 to 70 years
- Serum triacylglycerol \< 2.3 mmol/l
- Body mass index between 19-32 kg/m2
- Total cholesterol \< 7.5 mmol/l
Exclusion
- Females
- Smokers
- Medical history of myocardial infarction or stroke in the past 12 months
- Diabetes (defined as fasting glucose \> 7.0 mmol/l) or other endocrine disorders
- Kidney, liver, pancreas or gastrointestinal disorder
- Hypertension (blood pressure \> 140/90 mmHg), cancer, medication for hyperlipidaemia (e.g. statins), hypertension or, inflammation
- Anaemia (\<130 g/L haemoglobin)
- Taking any dietary supplements known to influence lipids/gut microbiota (e.g. plant stanols, fish oil, phytochemicals, natural laxatives, probiotics and prebiotics)
- Drinking in excess of 14 units of alcohol per week
- Planning on a weight-reducing regime
- Parallel participation in another dietary intervention study
- Any other unusual medical history or diet and lifestyle habits or practices that would preclude volunteers from participating in a dietary intervention and metabolic study
Key Trial Info
Start Date :
January 13 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2021
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT05264233
Start Date
January 13 2020
End Date
September 30 2021
Last Update
March 3 2022
Active Locations (1)
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1
Department of Food and Nutritional Sciences, University of Reading
Reading, Berkshire, United Kingdom, RG6 6AP