Status:

RECRUITING

PMCF Study to Evaluate Efficacy, Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects

Lead Sponsor:

Occlutech International AB

Conditions:

Patent Ductus Arteriosus

Eligibility:

All Genders

Brief Summary

This is a retrospective and prospective, multi-center, international, post marketing follow-up study to evaluate the safety and efficacy of the Occlutech PDA by using Occlutech Occlusions-Pusher (OOP)...

Detailed Description

Indication The Occlutech PDA Occluder is an occlusion system, which is percutaneously implanted through a catheter intervention technique and intended for the non-surgical occlusion of Patent Ductus A...

Eligibility Criteria

Inclusion

  • A patient of any age will be eligible for PDA closure if he or she meets the indication and area of application as laid down in the IFU. Thus, the Occlutech PDA Occluder is intended for the non-surgical occlusion of Patent Ductus Arteriosus (PDA).

Exclusion

  • Contraindications as laid down in the IFU:
  • Silent ductus or serious pulmonary hypertension:
  • Pulmonary Vascular Resistance (PVR) \> 8 Wood Units
  • Presence of a known coagulation disorder
  • Thrombus at the position allocated for the implantation
  • A vein thrombosis in the blood vessels chosen for the introducing system
  • An active infection (active endocarditis or other infections causing bacteremia) or history of endocarditis within 3 months from the procedure.
  • Nitinol intolerance (nickel or titanium)
  • Contrast medium intolerance
  • Patients who have a vascular system (which is used to access the defect) that is too small to admit the required sheath

Key Trial Info

Start Date :

December 20 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 25 2026

Estimated Enrollment :

255 Patients enrolled

Trial Details

Trial ID

NCT05264753

Start Date

December 20 2021

End Date

November 25 2026

Last Update

June 18 2023

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Ospedale Pediatrico Bambin Gesù

Roma, Italy, 00146

2

Rawalpindi Institute of Cardiology

Rawalpindi, Pakistan

3

Military Hospital

Tunis, Tunisia

4

Aydın Adnan Menderes University Hospital

Aydin, Efeler, Turkey (Türkiye)

PMCF Study to Evaluate Efficacy, Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects | DecenTrialz