Status:

COMPLETED

Is This PJI Really Acute: A Quantitative Sonication Fluid Analysis (Sonic)

Lead Sponsor:

University Hospital, Basel, Switzerland

Conditions:

Prosthetic-joint Infection

Eligibility:

All Genders

18+ years

Brief Summary

This retrospective study is to analyse microbiological cultures from the sonication fluid of the explanted prothesis to detect bacteria in the biofilm on the implant surface and to investigate whether...

Detailed Description

Implant associated infections in orthopaedics and trauma surgery are a well-known and feared complication. Prosthetic-joint infection (PJI) is caused by a biofilm which is located atop the surface of ...

Eligibility Criteria

Inclusion

  • patients who underwent a revision surgery of hip, knee and shoulder arthroplasties operated at the university hospital of Basel between 2011 and 2021,
  • patients who had a PJI as a suspected diagnosis and
  • have microbiological cultures from sonication fluid from removed prosthesis.

Exclusion

  • patients in the database who
  • have non-bacterial microbiological positive cultures (e.g. fungal infection) and
  • have not received a sonication of the removed prosthesis during the diagnostic process

Key Trial Info

Start Date :

June 30 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 31 2024

Estimated Enrollment :

176 Patients enrolled

Trial Details

Trial ID

NCT05265598

Start Date

June 30 2021

End Date

August 31 2024

Last Update

January 22 2025

Active Locations (1)

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Department of Orthopaedics and Traumatology, University Hospital Basel

Basel, Switzerland, 4031