Status:

COMPLETED

Use of Ibandronate in Diabetic Patients

Lead Sponsor:

Yeouido St. Mary's Hospital

Collaborating Sponsors:

Samsung Medical Center

Seoul National University Bundang Hospital

Conditions:

Osteoporosis, Postmenopausal

Type 2 Diabetes

Eligibility:

FEMALE

55+ years

Phase:

NA

Brief Summary

The purpose of this study is to examine whether monthly oral administration of ibandronate to postmenopausal osteoporosis patients with type 2 diabetes differs in safety and efficacy compared to patie...

Detailed Description

There are two major considerations in the use of bisphosphonates in diabetic patients. * The low rate of bone turnover in diabetic patients is at risk of side effects such as excessive inhibition of ...

Eligibility Criteria

Inclusion

  • age of at least 55 years at the time of screening
  • postmenopausal woman
  • diagnosis of osteoporosis

Exclusion

  • history of osteoporosis treatment
  • underlying disease (e.g., heart failure, liver disease, renal disease, or malignancy)
  • the use of drugs that affect bone metabolism (e.g., steroids, immunosuppressants, gonadotropin-releasing hormone agonists, aromatase inhibitors, thiazolidinedione drugs, anticonvulsants, and antidepressants)
  • history of adverse effects of bisphosphonate or difficulty taking the drug due to an inability to sit or the presence of upper gastrointestinal disease

Key Trial Info

Start Date :

October 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 31 2022

Estimated Enrollment :

121 Patients enrolled

Trial Details

Trial ID

NCT05266261

Start Date

October 1 2018

End Date

January 31 2022

Last Update

March 4 2022

Active Locations (1)

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Yeouido St.Mary's Hospital

Seoul, South Korea