Status:

UNKNOWN

Cost-effectiveness Analysis and Conditional Response to the Effect of Positional Devices in Obstructive Sleep Apnea

Lead Sponsor:

Hospital Universitario Ramon y Cajal

Collaborating Sponsors:

Philips Healthcare

Conditions:

Obstructive Sleep Apnea of Adult

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The objectives of this study are: * To assess the effectiveness and cost-effectiveness of a vibrating positional device (NightBalance, Philips) in the treatment of positional obstructive sleep apnea ...

Detailed Description

Non-inferiority clinical trial open to patients and investigators, multicenter, randomized and controlled to treatment with positional device (PD) and CPAP to evaluate the effectiveness of treatment o...

Eligibility Criteria

Inclusion

  • Patients over 18 years of age.
  • Signed informed consent.
  • Diagnosis of POSA by respiratory polygraphy with the following criteria:
  • AHI ≥ 15/h or AHI ≥ 10/h and AHI \<15/h with an Epworth \>10
  • AHI ns \<10/h (\<5/h in mild OSA).
  • AHI is at least twice the AHI in ns
  • Time in supine \>20%.
  • Valid recording time\>4h

Exclusion

  • Treatment of OSA with CPAP or DAM in the previous month or treatment with surgery for OSA at any time.
  • Presence of other sleep disorders or central sleep apnea (central AHI \>50% of total AHI).
  • Severe cardiovascular, neuromuscular or pulmonary pathology or chronic home oxygen use.
  • Poorly controlled arterial hypertension or refractory arterial hypertension.
  • Condition that makes it difficult or impossible to change position during sleep.
  • Epworth scale score ≥ 16.
  • Professional driver, heavy machinery operator or shift worker.
  • Pregnancy.
  • Treatment with medication that may interfere with alertness or drowsiness such as: sedative antidepressants, hypnotics, opioids, anticonvulsants or central nervous system stimulants.

Key Trial Info

Start Date :

October 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

154 Patients enrolled

Trial Details

Trial ID

NCT05268471

Start Date

October 1 2022

End Date

December 1 2024

Last Update

August 24 2022

Active Locations (1)

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1

Hospital Universitario Ramón y Cajal, Pneumology Department

Madrid, Spain, 28034