Status:

UNKNOWN

Inflammation in Tinnitus

Lead Sponsor:

University Medical Center Groningen

Conditions:

Tinnitus, Subjective

Tinnitus

Eligibility:

All Genders

18+ years

Brief Summary

Rationale: Tinnitus is the perception of sound without an external source. In the past decade, inflammation has been implicated in the pathophysiology of tinnitus. In animal models of tinnitus, the ex...

Eligibility Criteria

Inclusion

  • To be eligible to participate in this study, a subject must meet all of the following criteria:
  • Adult, aged 18 years or older;
  • Hearing threshold: average of 1000kHz, 2000kHz \& 4000kHz ≤ 25 dB.
  • Anxiety score HADS ≤ 7
  • Depression score HADS ≤ 7
  • Participant has sufficient mastery of the Dutch language to fill out the questionnaires.
  • Psychosocially, mentally, and physically able to fully comply with this protocol.

Exclusion

  • Objective tinnitus.
  • Presence of neurological disease (apart from tinnitus)
  • Presence of inflammatory disease, or the use of anti-inflammatory medication.
  • Presence or history of a malignancy
  • Presence of a disease of the ear (e.g. chronic otitis media, otosclerosis, previous surgery etc).
  • Presence of an coagulation disorder
  • Presence of a serious psychiatric disorder.
  • Pregnancy

Key Trial Info

Start Date :

March 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 1 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05268770

Start Date

March 1 2022

End Date

August 1 2022

Last Update

March 7 2022

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