Status:
UNKNOWN
Towards Early Detection of Breast Cancer in High Risk Population
Lead Sponsor:
University of Aberdeen
Conditions:
Breast Cancer
Eligibility:
FEMALE
18-55 years
Brief Summary
Breast cancer is a major and growing health challenge, and the leading cause of cancer in women. As population obesity rates increase, the number of new breast cancer diagnosis continues to rise. Desp...
Eligibility Criteria
Inclusion
- \-
- Women with BRCA1/2 genes:
- female 18-55 years old, premenopausal
- BRCA 1/2 gene carriers
- not having any metabolic disorders (e.g., diabetes)
- not on any long term medications that may affect lipid metabolism (e.g., statins)
- BMI \< 30
- Women with breast cancer (no obesity):
- females 18-55 years old, premenopausal
- confirmed diagnosis of invasive ductal carcinoma of the breast
- not having any metabolic disorders (e.g., diabetes)
- not on any long term medications that may affect lipid metabolism (e.g., statins)
- BMI \< 30
- Women with breast cancer (obesity):
- BMI \> 30
- otherwise as women with breast cancer
- Women with obesity:
- females 18-55 years old, premenopausal
- not having any metabolic disorders (e.g., diabetes)
- not on any long term medications that may affect lipid metabolism (e.g., statins)
- BMI \> 30
Exclusion
- females under 18 or over 55 years old, postmenopausal
- males
- have metabolic disorders (e.g., diabetes)
- on long term medications that may affect lipid metabolism (e.g., statins)
- contraindicated for MR investigation (poor renal function and metal implants)
- (for patients) concurrent cancer in other sites
- (for patients) started hormone treatment, chemotherapy or breast surgery
- non-English speakers
Key Trial Info
Start Date :
March 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2024
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05268913
Start Date
March 1 2022
End Date
May 1 2024
Last Update
March 7 2022
Active Locations (1)
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1
Aberdeen Biomedical Imaging Centre
Aberdeen, Aberdeenshire, United Kingdom, AB25 2ZD