Status:

COMPLETED

Aging and Frailty Study

Lead Sponsor:

Wake Forest University Health Sciences

Conditions:

Effects of Chemotherapy

Aging

Eligibility:

All Genders

65+ years

Brief Summary

The purpose of this research study is to compare methods to help personalize the prediction of chemotherapy side effects for older adults and to evaluate whether chemotherapy causes changes in the bod...

Detailed Description

Primary Objective: Describe mean and variation of the electronic frailty index-cancer, geriatric measures, patient reported outcomes, and biomarkers of aging of chemotherapy, and their change.

Eligibility Criteria

Inclusion

  • Age 65 years and older
  • Planned to initiate a new chemotherapy regimen
  • Solid tumor malignancy of any stage or lymphoma
  • Any performance status
  • Ability to understand and the willingness to sign an IRB-approved informed consent document (either directly or via a legally authorized representative).
  • Life expectancy of ≥3 months

Exclusion

  • Initiating biologic, endocrine or immunotherapy only.
  • Hematologic malignancy other than lymphoma.
  • Concurrent radiation therapy.
  • Planned inpatient chemotherapy.

Key Trial Info

Start Date :

May 2 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 13 2025

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT05268991

Start Date

May 2 2022

End Date

June 13 2025

Last Update

August 1 2025

Active Locations (1)

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1

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina, United States, 27157