Status:

COMPLETED

Association Between Ferroptosis and Epilepsy

Lead Sponsor:

Affiliated Hospital of Jiangnan University

Conditions:

Epilepsy

Eligibility:

All Genders

6-12 years

Brief Summary

Epilepsy is one of the most common neurologic disorders seen in children, often characterized by recurring seizures. Nearly 10.5 million children worldwide are estimated to have active epilepsy. Child...

Detailed Description

To investigate the possible association between GPX4 dependent ferroptosis pathway and epilepsy. Investigators first obtained gene expression of GSE25453 from GEO (https://www.ncbi.nlm.nih.gov/geo), w...

Eligibility Criteria

Inclusion

  • Seizure group
  • Aged between 6 and 12 years old
  • Newly diagnosed untreated epilepsy

Exclusion

  • Treated with medicine or another therapy
  • Had history of cancer diseases
  • Had history of endocrine diseases
  • Healthy control group
  • Inclusion Criteria:
  • 1\. Aged between 6 and 12 years old

Key Trial Info

Start Date :

January 20 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2022

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05269901

Start Date

January 20 2021

End Date

January 1 2022

Last Update

April 15 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Affiliated Hospital of JiangNan University, Department of Pediatrics

Wuxi, Jiangsu, China, 226600